A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This clinical study is testing whether a new combination of medicines (DSP107 and atezolizumab) is more effective and safer than an existing treatment (fruquintinib) for people with advanced colorectal cancer that is microsatellite stable (MSS). Participants will be randomly assigned to receive one of the two treatments, and researchers will monitor how well the cancer responds, how safe the treatments are, and how the body processes them. The study hopes to show that the new combination can improve outcomes for patients with this type of colorectal cancer.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat i spodziewana długość życia ponad 3 miesiące
- •Potwierdzony histologicznie rak jelita grubego w zaawansowanym stadium, który nie da się operować
- •Wcześniejsze leczenie nie więcej niż trzema liniami terapii
- •Mierzalne ogniska nowotworu widoczne w badaniach obrazowych
✗ Disqualifies
- •Przerzuty do mózgu, chyba że stabilne przez co najmniej 2 miesiące po leczeniu
- •Nieustąpione efekty uboczne drugiego stopnia lub wyższego z wcześniejszych terapii
- •Historia chorób autoimmunologicznych lub zaburzeń odporności
- •Inny nowotwór zdiagnozowany w ciągu ostatnich 3 lat
- •Uczulenie na składniki leku testowego
- •Nieprawidłowe wyniki badań laboratoryjnych mogące zagrozić bezpieczeństwu
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- August 20, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (18)
University of Colorado Hospital- Anschutz Cancer Center Pavillion (ACP)
Aurora, United States
University of Colorado Cancer Center - Highlands Ranch Hospital
Highlands Ranch, United States
Mayo Clinic
Florida City, United States
Duke University Medical Center - Duke Cancer Center
Durham, United States
UPMC Hillman Cancer Center
Pittsburgh, United States
The University of Texas MD Anderson Cancer Center
Texas City, United States
The Queen Elizabeth Hospital
Woodville, Australia
Chris O'brien Lifehouse
Camperdown, Australia
Port Macquarie Base Hospital (Mid North Coast Cancer Institute), Wrights Road,
Port Macquarie, Australia
Westmead Hospital
Westmead, Australia
Icon Cancer Centre
South Brisbane, Australia
Flinders Medical Centre SA
Bedford Park, Australia
Monash Health
Clayton, Australia
Footscray Hospital - Western Health
Footscray, Australia
Austin Health
Heidelberg, Australia
Alfred Hospital
Melbourne, Australia
Sunshine Hospital - Western Health
Saint Albans, Australia
Sir Charles Gairdner Hospital
Nedlands, Australia
Trial contact
Adam Foley Comer
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/13/2026.
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