A Study of Voice as a Way to Monitor for Side Effects in People Receiving CAR T-Cell Therapy
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The purpose of this study is to collect voice recordings and nervous system (neurologic) assessments from people with non-Hodgkin lymphoma (NHL) or multiple myeloma (MM) who are receiving standard treatment with CAR T-cell therapy. Researchers will study whether these voice recordings and assessments are a practical (feasible) way to monitor for immune effector cell-associated neurotoxicity syndrome (ICANS). Feasibility will be measured by tracking how many participants join the study and complete the assessments.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Rozpoznanie chłoniaka nieziarniczego lub szpiczaka wieloogniskowego potwierdzone badaniem patologicznym
- •Planowana terapia zatwierdzonym produktem CAR-T
- •Wiek co najmniej 18 lat
- •Zdolność do nagrywania głosu dwa razy dziennie przy użyciu smartfona
- •Zdolność do codziennych testów neurologicznych
- •Biegła znajomość angielskiego (do wykonywania zadań głosowych)
- •Posiadanie smartfona
✗ Disqualifies
- •Wcześniejsze choroby neurologiczne znacznie utrudniające mowę
- •Historia problemów z głosem lub mową, w tym porażenie strun głosowych
- •Patologia strun głosowych zakłócająca analizę głosu
- •Poważna niedosłyszalność utrudniająca ocenę głosu
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- August 6, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (8)
Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)
Basking Ridge, United States
Memorial Sloan Kettering Monmouth (Consent only)
Middletown, United States
Memorial Sloan Kettering Bergen (Consent Only)
Montvale, United States
Memorial Sloan Kettering Suffolk-Commack (Limited Protocol Activities)
Commack, United States
Memorial Sloan Kettering Westchester (Consent only)
Harrison, United States
Weill Cornell Medical Center (Data Analysis Only)
New York, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activites)
New York, United States
Memorial Sloan Kettering Nassau (Limited Protocol Activities)
Rockville Centre, United States
Trial contact
Roni Shouval, MD, PhD
Mohammad Alhomoud, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/7/2026.
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