A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This is a multicenter clinical study to evaluate the safety, efficacy, and Pharmacokinetics (PK) of IDE892 as monotherapy and in combination with other agents including IDE397 in participants with methylthioadenosine phosphorylase (MTAP)-deleted advanced solid tumors within indications of interest.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat
- •Potwierdzona diagnoza zaawansowanego nowotworu stałego z brakiem genu MTAP (określone typy nowotworów: opłucna, przełyku, żołądka, trzustki, dróg żółciowych, pęcherza moczowego lub płuca)
- •Dla niektórych pacjentów: nowotwór pęcherza moczowego lub płuca, który się pogorszył pomimo poprzedniego leczenia
- •Zdolność do przełykania tabletek i połykania leku
- •Dobrze funkcjonujące szpik kostny i narządy wewnętrzne
- •Spodziewana długość życia ponad 3 miesiące
- •Dobra ogólna kondycja zdrowotna (score ECOG 0-1)
- •Zgoda na pobranie próbek krwi i tkanki nowotworu do badań
✗ Disqualifies
- •Przerzuty do mózgu wymagające wysokich dawek sterydów
- •Pierwotny nowotwór ośrodkowego układu nerwowego (mózgu lub rdzenia kręgowego)
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- July 23, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (16)
Providence Medical Foundation
Santa Rosa, United States
Johns Hopkins Sibley Memorial Hospital
Washington D.C., United States
BRCR Global-Coral Springs
Coral Springs, United States
Sarah Cannon Research Institute at Florida Cancer Specialists
Orlando, United States
Nebraska Cancer Specialists
Omaha, United States
START Astera, LLC
East Brunswick, United States
Columbia University Irving Medical Center
New York, United States
Sidney Kimmel Comprehensive Cancer Center Thomas Jefferson University
Philadelphia, United States
Sarah Cannon Research Institute
Nashville, United States
START Dallas Fort Worth
Fort Worth, United States
MD Anderson
Houston, United States
NEXT Oncology Houston
Houston, United States
NEXT Oncology Dallas
Irving, United States
START Mountain Region, LLC
West Valley City, United States
NEXT Oncology Virginia
Fairfax, United States
Swedish Cancer Institute
Seattle, United States
Trial contact
IDEAYA Clinical Trials
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/9/2026.
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