Sparing Parotid Ducts Via MRI Sialography for Reduced Patient-Reported Xerostomia
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Radiation-induced xerostomia (dry mouth) is one of the most common and severe side effects for patients receiving radiation therapy for head and neck cancer. New approaches are needed to reduce this side effect and improve patients' quality of life after treatment. This is a Phase II, single-center, double-masked, parallel-arm, randomized controlled trial. It compares MRI-guided parotid ductal sparing to the standard approach of mean parotid gland sparing, focusing on patient-reported dry mouth outcomes in individuals receiving definitive radiotherapy for oropharyngeal cancer.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat
- •Rozpoznany rak gardła (orofarynksu) kwalifikujący się do radioterapii
- •Zgoda na uczestnictwo w badaniu i udostępnienie danych medycznych
- •Możliwość wykonania rezonansu magnetycznego (MRI)
- •Dobry stan ogólny zdrowia (ocena ECOG 0-2)
- •Kobiety w wieku rozrodczym muszą stosować skuteczną antykoncepcję
✗ Disqualifies
- •Wcześniejsza radioterapia głowy i szyi
- •Schorzenie Sjögrena lub wyjściowa suchość jamy ustnej
- •Zmiany nowotworowe w grucołach ślinowych
- •Alergia na sok cytrynowy
- •Ciąża lub karmienie piersią
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- October 13, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (1)
University of North Carolina at Chapel Hill, Department of Radiation Oncology
Chapel Hill, United States
Trial contact
Tuvara King
Melissa Knutsen
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/14/2026.
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