A Study of Pembrolizumab in Japanese Pediatric Participants With Solid Tumors or Lymphomas and Japanese Adult Participants With Merkel Cell Carcinoma (MK-3475-G21/KEYNOTE-G21)

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

Researchers are looking for new ways to treat people with solid tumors, lymphomas (blood cancers), and a certain type of skin cancer. The goals of this study are to learn: * About the safety of pembrolizumab (the study medicine) and if people tolerate it * What happens to different doses of pembrolizumab in a person's body over time * How the cancer responds (gets smaller or goes away) to treatment

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Potwierdzony nowotwór (chłoniak Hodgkina, chłoniak dużych komórek B w śródpiersiu, czerniak lub inny nowotwór stały)
  • Nowotwór widoczny w badaniach obrazowych
  • U dzieci z czerniakiem: nowotwór całkowicie usunięty chirurgicznie
  • U dorosłych z czerniakiem: nowotwór lokalnie zaawansowany lub dający przerzuty
  • Nowotwór nie poddawał się wcześniejszemu leczeniu lub leczenie nie zadziałało
  • U części pacjentów: badanie genetyczne pokazuje określone cechy nowotworu (MSI-H/dMMR lub TMB-H)

Simplified criteria — AI translation

Trial details

Minimum age
6 Months
Last updated (source)
July 13, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (7)

Nagoya City University Hospital ( Site 0003)

Nagoya, Japan

Nagoya City University Hospital ( Site 0007)

Nagoya, Japan

Sapporo Hokuyu Hospital ( Site 0005)

Sapporo, Japan

Hyogo Prefectural Kobe Children's Hospital ( Site 0006)

Kobe, Japan

National Cancer Center Hospital ( Site 0002)

Chūō, Japan

National Hospital Organization Kyushu Cancer Center ( Site 0001)

Fukuoka, Japan

University Hospital,Kyoto Prefectural University of Medicine ( Site 0004)

Kyoto, Japan

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/14/2026.

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