RecruitingPhase IEN originalLung cancerMetastatic / advanced

Study of NXP900 With Osimertinib in Subjects With Advanced, EGFR-Mutated Non-Small Cell Lung Cancer

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This is a multi-center, open label, Phase 1b study of NXP900 in combination with osimertinib in subjects with advanced, progressing, EGFR-mutated non-small cell lung cancer (NSCLC)

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Wiek 18 lat lub więcej
  • Potwierdzony zaawansowany rak płuca z mutacją EGFR, który nie można operować
  • Poprzednia terapia osimertynibem w terapii pierwszej lub drugiej linii
  • Stan ogólny pozwalający na leczenie (ECOG 0-1)
  • Chęć i możliwość udzielenia świadomej zgody na udział w badaniu

✗ Disqualifies

  • Rak spowodowany innym niż EGFR uszkodzeniem genetycznym
  • Mutacje EGFR powodujące odporność na osimertynib
  • Nadmierna ekspresja białka HER2 w komórkach raka
  • Jakiekolwiek przeciwwskazania do leczenia osimertynibem

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
July 9, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (6)

Maryland Oncology Hematology

Calverton, United States

Massachusetts General Hospital

Boston, United States

Willamette Valley Cancer Institute and Research Center

Eugene, United States

UPMC Hillman Cancer Center

Pittsburgh, United States

NEXT Houston

Houston, United States

NEXT Virginia

Fairfax, United States

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/10/2026.

You can help another person

We fund the Radar, this site, and the development of our Grosz dla Życia fundraising platform from donations and our own resources. Every contribution, even a small one, really helps.