SL-28 for Advanced Solid Tumours

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

Second Life Therapeutics is developing SL-28, an allogeneic, non-genetically modified cell-based therapy for the treatment of advanced solid tumours. The company has recently demonstrated a novel, non-genetic approach to modulate immune cell activity through targeted manipulation of the Universal Receptive System. The purpose of this open label, multi-center clinical trial is to evaluate the anti-tumor activity, safety, and pharmacokinetics, single-agent SL-28 in patients with a diverse array of solid tumors. The study includes an initial Phase 1 dose escalation to determine recommended dose(s) for expansion of SL-28 as a monotherapy and Phase 2 expansion cohorts. The study will enroll patients with advanced solid tumours, including those who failed previous lines of chemo- and immunotherapies.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Wiek co najmniej 18 lat
  • Oczekiwana długość życia co najmniej 3 miesiące
  • Potwierdzony zaawansowany rak (nieoperacyjny, przerzutowy lub rozprzestrzeniający się)
  • Rak, który nie odpowiedział na standardowe leczenie, immunoterapię lub leczenie ukierunkowane
  • Bądź w dobrym ogólnym stanie zdrowia (ECOG 0-1)
  • Prawidłowe funkcjonowanie wątroby, nerek i tworzącej się krwi
  • Dla kobiet: nie być w ciąży i używać antykoncepcji przez 90 dni po leczeniu
  • Dla mężczyzn: nie oddawać nasienia przez 90 dni po leczeniu

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
July 10, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

The Southern Oncology Clinical Research Unit (SOCRU)

Adelaide, Australia

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/10/2026.

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