RecruitingPhase IEN originalLeukemia

Venetoclax, Dexamethasone, Bortezomib, and Daratumumab For The Treatment Of Adolescent And Young Adults With Relapsed Or Refractory T-Cell Acute Lymphoblastic Leukemia And T-cell Acute Lymphoblastic Lymphoma

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This is an open-label, single institution, Phase 1 study of Venetoclax, Dexamethasone, Bortezomib, and Daratumumab for adolescent and young adult participants with relapsed or refractory T-ALL or T-LBL

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Wiek od 12 do 30 lat
  • Diagnoza potwierdzonych nawrotowych lub opornych na leczenie białaczek lub chłoniaków T-komórkowych
  • Masa ciała co najmniej 40 kg
  • Wystarczająca funkcja serca (frakcja wyrzutu co najmniej 40%)
  • Wystarczająca funkcja wątroby i nerek
  • Możliwość przyjmowania leków doustnie lub dożylnie
  • Brak zakaźnego HCV (hepatitis C), lub jeśli leczone - brak wirusa we krwi
  • Jeśli pacjent ma HBV (zapalenie wątroby B) - wirus musi być suppressowany lekami

Simplified criteria — AI translation

Trial details

Minimum age
12 Years
Maximum age
30 Years
Last updated (source)
August 12, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

UT MD Anderson

Houston, United States

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/13/2026.

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