Study of High-Precision Evaluation of Molecular ResiduaL Disease Through a PlatfOrm for Cancer TracKing and Interception (SHERLOCK)

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This study will collect, annotate, and sequence biospecimens (blood, tissue, urine, saliva and surgery drainage) from patients across different cancer types to detect molecular residual disease (MRD). Imaging scans and clinical data will also be gathered. This will allow for early cancer interception, and hopefully prolong relapse-free survival across tumor types. Results of ctDNA testing will be provided for clinical decisions and to determine eligibility for other linked interventional interception therapeutic studies, each of which will have a separate protocol.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Potwierdzony rozpoznaniem raka (badanie histologiczne, cytologia lub charakterystyczne obrazy/markery biologiczne)
  • Ukończone leczenie raka w zamierzeniu wyleczenia (operacja, napromienianie, chemioterapia, kombinacje) w ciągu ostatnich 12 miesięcy
  • Wiek co najmniej 18 lat
  • Podpisana i datowana świadoma zgoda na udział w badaniu

✗ Disqualifies

  • Inny aktywny nowotwór rozpoznany w ciągu ostatnich 2 lat (oprócz raka skóry i raka szyjki macicy we wczesnym stadium)
  • Przeszczepienie macierzystych komórek krwi od innego dawcy w przeszłości

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
May 11, 2026
Sex
No restrictions

Locations (1)

Princess Margaret Hospital

Toronto, Canada

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/1/2026.

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