RecruitingPhase I/IIMale onlyEN originalProstate cancerMetastatic / advanced

A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Activity of GDC-1261 in Participants With Advanced or Metastatic Prostate Cancer

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The purpose of this study is to evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-1261 in participants with advanced or metastatic prostate cancer. It's also to identify a recommended dose(s) and regimen for GDC-1261 for subsequent studies.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Pacjent ma dobry stan ogólny (zdolny do lekkich czynności)
  • Oczekiwana długość życia co najmniej 3 miesiące
  • Potwierdzony diagnozą rak gruczołu krokowego
  • Nowotwór się rozprzestrzenił do innych części ciała
  • Pacjent otrzymuje leczenie hormonalne prostaty
  • Dobra funkcja nerek, wątroby i serca

✗ Disqualifies

  • Pacjent otrzymywał inną chemioterapię w ostatnich 14 dniach
  • Przerzuty w mózgu bez leczenia
  • Silny ból, który nie jest kontrolowany
  • Inne nowotwory w ciągu ostatnich 5 lat
  • Aktywna infekcja wymagająca antybiotyków

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
July 9, 2026
Sex
Male only

Therapies / drugs in trial

Locations (4)

Honor Health Research Institute

Scottsdale, United States

Sarah Cannon Research Institute

Nashville, United States

St Vincent's Hospital Sydney

Darlinghurst, Australia

Austin Hospital

Heidelberg, Australia

Trial contact

Reference Study ID Number: GO46445 https://forpatients.roche.com/ No attachments to email below.

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/10/2026.

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