RecruitingPhase IIEN originalHead and neck cancer

Nimotuzumab Combined With Immunotherapy and Chemotherapy in the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This is a randomized controlled, phase II clinical study designed to explore the efficacy and safety of nimotuzumab combined with immunotherapy and chemotherapy as neoadjuvant treatment for locally advanced head and neck squamous cell carcinoma (LA-HNSCC). The primary endpoint of the study is the 2-year event-free survival (EFS) rate. Enrollment is expected to be completed within 2 years; all patients will be followed up for at least 2 years after the last patient is enrolled.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Wiek od 18 do 75 lat
  • Potwierdzony rak płaskonabłonkowy głowy i szyi (badanie mikroskopowe)
  • Nowotwór można usunąć chirurgicznie (ocena zespołu specjalistów)
  • Dobry ogólny stan zdrowia (ECOG 0-1)
  • Dostępna próbka guza do badań laboratoryjnych
  • Co najmniej jedno widoczne ognisko nowotworu
  • Oczekiwana długość życia co najmniej 6 miesięcy
  • Prawidłowe wyniki badań krwi, nerek i wątroby

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Maximum age
75 Years
Last updated (source)
July 9, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

Shanghai First People's Hospital

Shanghai, China

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/10/2026.

You can help another person

We fund the Radar, this site, and the development of our Grosz dla Życia fundraising platform from donations and our own resources. Every contribution, even a small one, really helps.