CD70-Targeted Immuno-PET/CT-Directed Free of Therapy Used for mccRCC Patients With IMDC Favorable or Intermediate Risk
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The purpose of this study is to evaluate the safety and feasibility of a treatment holiday strategy directed by CD70-targeted immuno-PET/CT in patients with metastatic clear cell renal cell carcinoma (mccRCC). Specifically, the study aims to assess whether patients who achieve both anatomical disease control and metabolic response after 12 months of first-line PD-1/PD-L1 ICI + VEGFR-TKI combination therapy can safely pause their treatment, improve quality of life without compromising therapeutic efficacy.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek 18 lat lub więcej
- •Zaawansowany rak nerki z przerzutami (stadium IV), który nie może być operacyjnie usunięty
- •Potwierdzone histologicznie lub cytologicznie zaawansowane nowotwory nerki, głównie typu jasnokomórkowego
- •Ocena ryzyka klinicznego pośrednia lub korzystna
- •Ogólny stan zdrowia pozwalający na aktywność (co najmniej 70% sprawności)
- •Co najmniej jedno widoczne ognisko nowotworu na tomografii
- •Prawidłowe wyniki badań krwi i funkcji narządów wewnętrznych
- •Podpisana świadoma zgoda na udział w badaniu
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- July 23, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (5)
Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University
Nanjing, China
Nanjing First Hospital, Nanjing Medical University
Nanjing, China
The First Affiliated Hospital of Nanjing Medical University
Nanjing, China
Sir Run Run Hospital, Nanjing Medical University
Nanjing, China
Wuxi No.2 People's Hospital (Jiangnan University Medical Center)
Wuxi, China
Trial contact
Le Qu, Ph.D.
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/24/2026.
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