BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The objective of the study is to evaluate the efficacy and safety of BL-M14D1 in combination with Atezolizumab compared to Standard-of-Care Therapy in adult participants with previously untreated extensive-stage small cell lung cancer (ES-SCLC).
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Potwierdzona diagnoza zaawansowanego raka płuca z małymi komórkami (pierwszy raz rozpoznanego)
- •Kwalifikacja do chemioterapii opartej na platynie w połączeniu z lekiem przeciwko PD-L1
- •Obecność przynajmniej jednego mierzalnego ogniska nowotworu
- •Ogólny stan zdrowia oceniony na 0-1 w skali ECOG
- •Prawidłowe funkcjonowanie organów wewnętrznych
✗ Disqualifies
- •Wcześniejsze leczenie platyną lub etopozyd em w ciągu ostatnich 6 miesięcy
- •Wcześniejsze stosowanie terapii ADC opartej na inhibitorach topoisomerazy
- •Poważne choroby serca w przeszłości
- •Aktywne choroby autoimmunologiczne lub zapalne
- •Inne nowotwory (z wyjątkiem łagodnych nowotworów skóry) lub inne nowotwory leczone curacyjnie przed mniej niż 3 laty
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 17, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (62)
Highlands Oncology Group
Springdale, United States
Los Alamitos Hematology/Oncology Medical Group
Glendale, United States
MemorialCare Todd Cancer Institute
Long Beach, United States
Valkyrie Clinical Trials
Los Angeles, United States
Total Health and Research Center
Miami, United States
Astera Cancer Care
East Brunswick, United States
Virginia Cancer Specialists
Fairfax, United States
Canberra Hospital
Garran, Australia
Tasman Oncology
Southport, Australia
Flinders Medical Centre
Bedford Park, Australia
MHAT Dr. Tota Venkova
Gabrovo, Bulgaria
MHAT Heart and Brain
Pleven, Bulgaria
Medical Centre FutureMeds
Plovdiv, Bulgaria
MHAT Pulmed
Plovdiv, Bulgaria
UMHAT Sveti Ivan Rilski
Sofia, Bulgaria
MHAT Serdikamed
Sofia, Bulgaria
Arthur Child Cancer Centre
Calgary, Canada
University of Sherbrooke
Greenfield Park, Canada
Nemocnice České Budějovice, a.s.
České Budějovice, Czechia
Nemocnice Agel Vítkovice
Ostrava, Czechia
Fakultní nemocnice Ostrava (FN Ostrava)
Ostrava-Poruba, Czechia
Organization Centre Hospitalier Intercommunal de Creteil (CHIC) - Centre de Recherche Clinique (CRC) (Clinical Research Center)
Créteil, France
CLB - Centre Léon Bérard
Lyon, France
IPC - lnstitut Paoli-Calmettes
Marseille, France
Universite Pierre et Marie Curie (UPMC) - Center de Recherche des Cordeliers (CRC)
Paris, France
ICO - L'Institut de Cancérologie de L'Ouest
Saint-Herblain, France
LTD High Technology Hospital Medcenter
Tbilisi, Georgia
Ltd New Hospitals
Tbilisi, Georgia
Pineo Medical Ecosystem LtD
Tbilisi, Georgia
LLC Todua Clinic
Tbilisi, Georgia
The First Medical Clinic LLC
Tbilisi, Georgia
Caucasus Medical Centre
Tbilisi, Georgia
Lungenklinik/Lungenkrebszentrum Köln-Merheim
Cologne, Germany
KEM | Evangelische Kliniken Essen Mitte gGmbH
Essen, Germany
Krankenhaus Martha-Maria Halle-Dölau
Halle, Germany
Henry Dunant Hospital Center
Athens, Greece
Theageneio Anticancer Hospital
Thessaloniki, Greece
St Luke's Hospital
Thessaloniki, Greece
European Interbalkan Medical Center
Thessaloniki, Greece
Semmelweis University Department of Pulmonology
Budapest, Hungary
Mátrai Gyógyintézet
Gyöngyös, Hungary
Bács-Kiskun Vármegyei Oktatókórház, Oncoradiology Center
Kecskemét, Hungary
Református Pulmonológiai Intézet
Törökbálint, Hungary
Centro di Riferimento Oncologico
Aviano, Italy
Policlinico Paolo Giaccone University Hospital
Palermo, Italy
Regina Elena Institute for Cancer Research
Roma, Italy
Fondazione Policlinico Universitario A. Gemelli IRCCS
Roma, Italy
AOUS Le Scotte, UOC Immunoterapia Oncologica
Siena, Italy
Uniwersytecki Szpital Kliniczny w Bialymstoku, II Klinika Chorob Pluc, Raka Pluca i Chorob Wewnetrznych
Bialystok, Poland
Szpitale Pomorskie Spolka z ograniczona odpowiedzialnoscia, Oddzial Onkologii i Radioterapii - Dzial Onkologii Klinicznej
Gdynia, Poland
Oddzial Onkologii Klinicznej
Katowice, Poland
Instytut "Centrum Zdrowia Matki Polki", Klinika Onkologii
Lodz, Poland
Szpital Specjalistyczny w Prabutach Spolka z ograniczona odpowiedzialnoscia, Oddzial pulmonologii
Prabuty, Poland
University Clinical Centre of Serbia, Clinic for pulmonology
Belgrade, Serbia
University Hospital Medical Center Bezanijska Kosa
Belgrade, Serbia
University Clinical Center Kragujevac
Kragujevac, Serbia
Institute for pulmonary diseases of Vojvodina
Novi Sad, Serbia
Complejo Hospitalario Universitario A Coruna (CHUAC) - Hospital Teresa Herrera
A Coruña, Spain
Hospital de la Santa Creu i Sant Pau
Barcelona, Spain
Hospital Universitario Insular de Gran Canaria
Las Palmas de Gran Canaria, Spain
Hospital Clinico San Carlos
Madrid, Spain
Centro de Investigación Oncológica Clara Campal
Madrid, Spain
Trial contact
Loren VanPelt
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/16/2026.
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