Impact of HMB Supplementation on Inflammation and Outcomes in Head and Neck Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Cancer patients undergoing surgery are at high risk of malnutrition due to the effects of the tumor and surgical stress, which can lead to worse clinical outcomes. This study aims to evaluate the impact of beta-hydroxy-beta-methylbutyrate (HMB) supplementation on inflammatory markers and clinical outcomes in patients with malignant tumors of the upper airways and digestive tract undergoing surgery. This is a randomized, double-blind clinical trial. Participants will be randomly assigned to one of two groups: intervention (3 g/day of HMB) or control (3 g/day of maltodextrin) for 30 days prior to surgery. Initial assessments will include nutritional status, muscle strength, quadriceps muscle thickness by ultrasound, and laboratory tests. Postoperative clinical outcomes will be monitored through electronic medical records.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Osoby w wieku 18 lat lub starsze.
- •Mężczyźni i kobiety.
- •Pacjenci leczeni ambulatoryjnie z powodu raka głowy i szyi.
- •Pacjenci zakwalifikowani do operacyjnego usunięcia guza w celu wyleczenia.
✗ Disqualifies
- •Rak twarzy, skóry, zatok przynosowych lub tarczycy.
- •Przyjmowanie leczenia przed operacją (neoadjuwantowego) lub łagodzącego objawy (paliatywnego).
- •Trudności ze zrozumieniem zasad badania z powodu problemów z pamięcią lub intelektualnych.
- •Niechęć do udziału w badaniu lub podpisania zgody.
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- June 30, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (1)
School of Medicine, Federal University of Minas Gerais
Belo Horizonte, Brazil
Trial contact
Marcus Vinícius M Andrade, MD, PhD
Simone V Generoso, PhD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/3/2026.
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