Clonal Hematopoiesis Chemotherapy and Radiation Effects Study
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The goal of the Clonal Hematopoiesis Chemotherapy and Radiation Effects (CH CARE) Study is to understand how the presence or absence of clonal hematopoiesis (CH) influences outcomes in people receiving chemotherapy and radiation for solid cancers. The study will collect biospecimens and clinical information. These data will be used to define clinical and molecular features that predict the presence of high-risk clonal hematopoiesis (CH) in patients exposed to cytotoxic anti-cancer therapy. Predictive features will be utilized to identify populations of cancer patients and survivors who are at the highest risk of developing therapy-related myeloid neoplasms (t-MNs). Ultimately this study will result in the development of a novel novel risk prediction algorithm for t-MNs in patients with solid cancers and drive potential therapeutic approaches to intercept progression from CH to often fatal t-MNs.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Osoby powyżej 18. roku życia.
- •Zdiagnozowany rak innego narządu (np. piersi, płuca, jelita).
- •Planowane leczenie raka chemioterapią lub radioterapią.
- •Nieotrzymanie wcześniej chemioterapii ani radioterapii z powodu obecnego raka.
✗ Disqualifies
- •Osoby nieplanujące chemioterapii, radioterapii ani leczenia lekami z grupy inhibitorów PARP.
- •Osoby, które już otrzymały chemioterapię lub radioterapię z powodu obecnego raka.
- •Osoby z jakąkolwiek historią choroby krwi (np. białaczka, chłoniak).
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- June 30, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (1)
Dana-Farber Cancer Institute
Boston, United States
Trial contact
Cindy Amaya Lopez, BA
Jenna Beckwith, MPH
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/3/2026.
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