PROV-MESH: Prophylactic Ovarian Cancer MESH
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Incisional hernia is a common complication after midline laparotomy and may significantly impact quality of life, morbidity, and healthcare costs. Patients undergoing cytoreductive surgery for ovarian cancer are considered at increased risk due to extensive surgical procedures, nutritional status, and exposure to systemic treatments. This prospective randomized clinical trial aims to evaluate whether prophylactic mesh placement during abdominal wall closure reduces the incidence of incisional hernia compared with conventional fascial closure in women undergoing cytoreductive surgery for ovarian cancer through a midline laparotomy. To control for the potential effect of negative pressure wound therapy (NPWT) on surgical site infection, participants will also be randomized to receive NPWT or standard wound dressing, resulting in four treatment arms.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Kobiety z rakiem jajnika.
- •Podchodzące do pierwszej operacji, operacji po chemioterapii lub drugiej operacji.
- •Operacja wykonywana przez długie nacięcie na środku brzucha.
- •Chęć i możliwość podpisania zgody na udział w badaniu.
✗ Disqualifies
- •Operacje z powodu nawrotu raka jajnika.
- •Operacje wykonywane małoinwazyjnie (przez małe nacięcia).
- •Planowana kolejna operacja w ciągu 2 lat.
- •Niezdolność lub brak chęci do przestrzegania zaleceń dotyczących wizyt kontrolnych.
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- June 30, 2026
- Sex
- Female only
Therapies / drugs in trial
Locations (1)
Hospital Universitario Vall d'Hebron
Barcelona, Spain
Trial contact
Jose Luis Sánchez Iglesias, MD PhD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/3/2026.
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