Phase 1 Study of NTB-928 in R/R OC
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The goal of this clinical trial is to determine if NTB-928 can be given safely to adult females with ovarian cancer that has come back (relapsed) or stopped responding to treatment (refractory), how NTB-928 moves through the body, and how the immune system reacts to it. The study will also look for early signs of anti-cancer activity of NTB-928. The main questions the study aims to answer are: * What side effects do participants experience when receiving NTB-928, including side effects that limit how much of it can be safely given? * How is NTB-928 processed by the body at different dose levels? * Does the immune system react to NTB-928 during treatment? * What dose of NTB-928 can be given safely that shows early signs of activity against ovarian cancer?
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek 18 lat lub więcej
- •Potwierdzony diagnozą rak jajnika (określone typy)
- •Rak jajnika, który wrócił lub nie reaguje na leczenie, pomimo wcześniejszych standardowych terapii
- •Rozumienie wymagań badania i chęć podpisania zgody
- •Chęć stosowania skutecznej antykoncepcji podczas badania i przez okres po jego zakończeniu (jeśli jest możliwość zajścia w ciążę)
✗ Disqualifies
- •Inne aktywne nowotwory, które mogą wpłynąć na wyniki badania
- •Wcześniejsze otrzymywanie innych eksperymentalnych leków lub określonych terapii onkologicznych
- •Ciąża lub karmienie piersią
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- July 10, 2026
- Sex
- Female only
Therapies / drugs in trial
Locations (2)
START Northwell, LLC
Lake Success, United States
Start Ccbd, Llc
Fort Worth, United States
Trial contact
Clinical Trial Information
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/9/2026.
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