MELanoma Brain Metastasis Treated With CYberknife
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Melanoma is a type of cancer that can spread to the brain, making the disease harder to treat and worsening both survival and quality of life. In recent years, treatments have improved significantly thanks to advances in surgery, radiotherapy, immunotherapy, and targeted therapy. These new treatments have greatly increased survival rates for patients with metastatic melanoma. This study focuses on stereotactic radiosurgery, a highly precise form of radiotherapy used to treat brain metastases. Researchers want to better understand how this treatment works when combined with immunotherapy or targeted therapy, and whether the timing and sequence of treatments can improve outcomes. Between 2026 and 2028, patients treated at the IEO for melanoma brain metastases will be observed and their clinical data collected. The goal is to improve future treatment strategies and help doctors choose the best therapeutic approach for each patient.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek powyżej 18 lat
- •Przerzuty czerniaków do mózgu potwierdzone badaniem MRI lub CT
- •Przerzuty mogą być leczone promieniowaniem precyzyjnym
- •Zgoda na udział w badaniu i leczeniu
✗ Disqualifies
- •Nowotwór rozprzestrzeniony na opony mózgowe
- •Wcześniejsze leczenie całej głowy promieniowaniem lub operacja przerzutów
- •Czerniak z innych części ciała niż skóra (np. z oka)
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 10, 2026
- Sex
- No restrictions
Locations (2)
European Institute of Oncology, Milan
Milan, Italy
European Institute of Oncology, Milan
Milan, Italy
Trial contact
Samantha Dicuonzo, MD
Lorenzo Colombi, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/11/2026.
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