A Study to Assess Safety and Efficacy of SOT109 in Patients With Advanced Unresectable or Metastatic Colorectal Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
SOT109 is a special cancer medicine designed to find and kill certain cancer cells that carry a marker called CDH17, while causing less harm to healthy cells. The study consists of two parts, Part A and Part B. The goal of Part A is to collect information about SOT109, understand its effects, and see whether it is safe and well tolerated at different dose levels. Part B of the study collects information on which of the two selected safe dose levels chosen in Part A gives the best balance between benefit and risk.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek 18 lat lub więcej
- •Potwierdzona zdolność do zrozumienia i podpisania zgody na uczestnictwo
- •Dobry ogólny stan zdrowia (ECOG 0-1)
- •Przewidywana długość życia co najmniej 3 miesiące
- •Zaawansowany lub przerzutowy rak jelita grubego potwierdzona badaniem mikroskopowym
- •Wcześniejsze leczenie standardowymi chemioterapiami (fluoropiramidyny, oksaliplatyna, irinotekan, bevacizumab)
- •Odpowiednie wyniki badań krwi i funkcji wątroby
- •Prawidłowa funkcja serca (frakcja wyrzutu lewej komory ≥50%)
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 21, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (3)
NEXT Houston
Houston, United States
NEXT Virginia
Faifax, United States
Arensia Exploratory Medicine Research Unit, Institute of Oncology
Chisinau, Moldova
Trial contact
Richard Kapsa
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/22/2026.
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