A Novel Clinical Decision Support Tool to Predict Submucosal Invasive Cancer Within Large Non-Pedunculated Colorectal Polyps
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Colorectal cancer can be effectively prevented by removal of pre-malignant polyps during colonoscopy. Large (\>=20mm) non-pedunculated colorectal polyps (LNPCPs) require careful assessment before treatment. If submucosal invasive cancer (SMI) is present, it determines whether endoscopic treatment can be curative or whether surgery is needed. Current classification systems to detect SMI are complex, require extensive training, and are underused in non-tertiary hospitals. A simple web-based clinical decision support tool was created using well-established parameters (presence of a demarcated area, polyp size, Paris classification, location, and granularity) to identify SMI within LNPCPs. Crucially, the tool uses only standard endoscopic imaging available in most endoscopy units. This prospective multi-centre study evaluates the accuracy of the tool during live endoscopic assessment. Endoscopists of varying experience will assess 10 large colorectal polyps using the tool, then undergo a randomized educational intervention (either a 10-minute instructional video or a 45-minute interactive training session). They will then assess a further 10 polyps using the tool. A third set of 10 assessments at 3 months evaluates durability of learning. Accuracy is compared to expert opinion.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Lekarze specjaliści wykonujący endoskopię przewodu pokarmowego (różne doświadczenie zawodowe)
- •Lekarze, którzy wcześniej nie stosowali tego narzędzia
- •Pacjenci skierowani na kolonoskopię z prawidłowym przygotowaniem jelita
- •Polip jelita grubego o rozmiarze co najmniej 20 mm
- •Polip o budowie niepedunkulowanej (bez szypułki)
- •Pacjenci, którzy wyrazili pisemną zgodę na wykonanie badania i uczestnictwo w badaniu
✗ Disqualifies
- •Lekarze, którzy nie wyrażają zgody na uczestnictwo
- •Lekarze, którzy nie odbyją sesji szkoleniowej
- •Pacjenci, którzy nie wyrażają zgody na gromadzenie danych
- •Zarejestrowany niedostatecznej jakości obraz z kamery endoskopowej
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- July 15, 2026
- Sex
- No restrictions
Locations (1)
UZ Gent
Ghent, Belgium
Trial contact
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/16/2026.
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