Transperineal Versus Transrectal Cognitive Fusion Prostate Biopsy
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This prospective randomized controlled trial aims to compare transperineal and transrectal cognitive fusion prostate biopsy techniques in patients with suspicious prostate lesions detected by multiparametric magnetic resonance imaging (mpMRI). Patients aged 50-75 years with PI-RADS 3-5 lesions on mpMRI and an indication for prostate biopsy will be randomly assigned in a 1:1 ratio to undergo either transperineal cognitive fusion prostate biopsy or transrectal cognitive fusion prostate biopsy. The primary objective of this study is to evaluate whether transperineal cognitive fusion biopsy is non-inferior to transrectal cognitive fusion biopsy in detecting clinically significant prostate cancer (csPCa). Secondary objectives include comparison of overall prostate cancer detection rates, detection of Gleason Grade Group ≥2 prostate cancer, biopsy-related infectious complications, other procedure-related complications, pain scores, and procedure duration. A total of 280 participants will be enrolled. Pathological evaluation will be performed after biopsy, and clinical outcomes and complications will be assessed during follow-up.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Mężczyźni w wieku 50-75 lat
- •Niepokojące obszary w prostatie widoczne w badaniu MRI
- •Wskazanie do wykonania biopsji prostaty
- •Chęć udziału i zgodna na uczestnictwo
✗ Disqualifies
- •Wcześniejszy diagnoza raka prostaty
- •Aktywne zakażenie układu moczowego
- •Zaburzenia krzepnięcia lub склonność do krwawień
- •Brak wykonanego badania MRI prostaty
Simplified criteria — AI translation
Trial details
- Minimum age
- 50 Years
- Maximum age
- 75 Years
- Last updated (source)
- July 17, 2026
- Sex
- Male only
Therapies / drugs in trial
Locations (1)
Ankara Etlik City Hospital
Ankara, Turkey (Türkiye)
Trial contact
MUHAMMED Y AYDIN, Doctor
ALPER G GÖK, PROFESSOR DOCTOR
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/18/2026.
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