A Phase 1 Dose-escalation Study of UGN-501 Administered Intravesically in Adult Participants With Recurrent NMIBC
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This study is being conducted to evaluate the safety and tolerability of UGN-501 administered intravesically in adult participants with recurrent non-muscle invasive bladder cancer (NMIBC) and to determine the recommended Phase 2 dose (RP2D).
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat
- •Potwierdzony nawracający rak pęcherza moczowego (typ pogranicznej inwazji)
- •Choroba oporna na leczenie BCG lub osoby, które nie mogą tego leczenia tolerować
- •Wcześniejsze leczenie chirurgiczne - usunięcie widocznych guzów
- •Chęć uczestnictwa w badaniu i podpisanie zgody
✗ Disqualifies
- •Poniżej 18 lat
- •Rak pęcherza z przeniknięciem głębokich warstw mięśnia
- •Przerzuty nowotworu poza pęcherz
- •Ciężkie zaburzenia funkcji nerek lub wątroby
- •Poważne infekcje lub aktywne schorzenia utrudniające uczestnictwo w badaniu
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- October 13, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (15)
East Valley Urology Center of Arizona
Queen Creek, United States
Michael G Oefelein Clinical Trials
Bakersfield, United States
Urology Center of Southern California
Murrieta, United States
University of Colorado Cancer Center
Aurora, United States
University of Miami
Miami, United States
Brigham and Women's Hospital
Boston, United States
Michigan Institute of Urology
Troy, United States
University of Nebraska Medical Center
Omaha, United States
SUNY Upstate Medical University
Syracuse, United States
Oregon Health & Science University
Portland, United States
University of Pennsylvania-Perelman Center for Advanced Medicine
Philadelphia, United States
START Carolinas
Myrtle Beach, United States
UPNT Research Institute
Arlington, United States
Urology Austin
Austin, United States
Renovatio Clinical
The Woodlands, United States
Trial contact
Heather Lansford
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/14/2026.
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