Hyperpolarized 13C-MRI and Radiomics in Rectal Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This study is testing new imaging and analysis methods to improve how doctors predict treatment response in rectal cancer patients receiving chemoradiotherapy. Current MRI scans sometimes miss complete tumor response, which can lead to unnecessary surgery. To address this, researchers will use a special MRI technique called hyperpolarized carbon-13 MRI, along with blood and tissue analysis (metabolomics) and advanced image feature analysis (radiomics). These tools can track how cancer cells use energy and how metabolism changes during treatment. The study will follow 30 rectal cancer patients at Chang Gung Memorial Hospital over 3 years. Patients will undergo standard MRI, colonoscopy, and advanced metabolic imaging before and after treatment. Results will compare patients whose tumors completely respond to therapy with those who do not. The goal is to see if metabolic changes detected by hyperpolarized MRI and metabolomics can predict treatment outcomes earlier and more accurately. This may help doctors avoid unnecessary surgery and provide more personalized care for rectal cancer patients.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Diagnoza raka odbytnicy potwierdzona biopsją
- •Kwalifikacja do chemioterapii z promieniowaniem
- •Wiek powyżej 20 lat
✗ Disqualifies
- •Niemożliwość wykonania MRI (metal w ciele, klaustrofobia)
- •Aktywne infekcje lub poważne choroby serca
- •Zaburzenia psychiczne wpływające na możliwość uczestnictwa
- •Poważne problemy z wątrobą
- •Poważne problemy z nerkami
Simplified criteria — AI translation
Trial details
- Minimum age
- 20 Years
- Last updated (source)
- July 28, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (1)
Chang Gung Memorial hospital
Taoyuan, Taiwan
Trial contact
Ying-Chieh Lai, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/29/2026.
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