A COhort Study on Factors Leading to Vulnerability in Adult Patients With Serious Medical cOnditionS: the COSMOS-I Trial
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The objective of this prospective multicentre study that recruits altogether 1500 older patients from the university hospitals of Tampere, Kuopio, and Oulu is to explore the clinical significance and detection of causes of generalized vulnerability. The objectives are: O1 - Establish the prevalence of causes of generalized vulnerability among patients diagnosed with severe yet non-malignant diseases and local/locally advanced and advanced cancers, O2 - Study how causes of generalized vulnerability affect the time between the diagnosis and the adoption of a fully palliative treatment line, overall survival, and patient-reported quality of life in older adults severe diseases, and O3 - Evaluate how screening tools commonly used in patients without cancer perform in screening for causes of vulnerability in older adults with cancer
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Pacjenci z podejrzeniem lub zdiagnozowaną chorobą.
- •Osoby w wieku 60 lat i starsze (wyjątek: pacjenci po chemioterapii wysokodawkowej lub przeszczepie komórek macierzystych mogą mieć od 18 lat).
- •Wyniki badań obrazowych (np. tomografia) wykonane nie wcześniej niż 45 dni przed wyrażeniem zgody lub przed rozpoczęciem kolejnego etapu leczenia.
- •Pacjenci z innymi schorzeniami: badania muszą być wykonane nie później niż 4 dni po rozpoczęciu hospitalizacji.
✗ Disqualifies
- •Osoby, które nie mogą lub nie chcą udzielić pisemnej zgody na udział w badaniu.
- •Pacjenci, których badacz uzna za nieodpowiednich do udziału w badaniu.
Simplified criteria — AI translation
Trial details
- Last updated (source)
- July 31, 2026
- Sex
- Male only
Therapies / drugs in trial
Locations (1)
Tampere University Hospital
Tampere, Finland
Trial contact
Otso Arponen, Adjunct professor, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/1/2026.
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