Effect of Orlistat on Metabolic and Hormonal Features in Women With Polycystic Ovary Syndrome (PCOS): a Randomized Controlled Clinical Trial
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This randomized controlled clinical trial aims to evaluate the effect of orlistat on the metabolic and hormonal features of women with polycystic ovary syndrome (PCOS). Eligible women diagnosed with PCOS according to the Rotterdam criteria will be randomly assigned to receive either orlistat plus standard lifestyle advice or placebo plus standard lifestyle advice for three months. The study will assess the effect of orlistat on hormonal parameters, glucose metabolism, lipid profile, liver function, anthropometric measures, non-alcoholic fatty liver disease, and quality of life to determine its effectiveness as an adjunctive treatment for women with PCOS.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Kobieta w wieku 18-45 lat
- •Potwierdzony zespół policystycznych jajników (PCOS)
- •Nieregularne lub brak miesiączki
- •Oznaki wysokiego poziomu męskich hormonów
- •Policystyczne jajniki widoczne w USG
- •Wskaźnik masy ciała między 18,5 a 35 kg/m²
✗ Disqualifies
- •Stosowanie tabletek antykoncepcyjnych lub leków na owulację w ostatnim czasie
- •Stosowanie leków na cholesterol, otyłość lub suplementów wpływających na hormony
- •Leczenie niepłodności metodą in vitro (IVF)
- •Choroby nerek lub wątroby
- •Cukrzyca, zaburzenia tarczycy lub inne endokrynologiczne schorzenia
- •Ciąża, karmienie piersią lub menopauz
- •Zbyt niski poziom AMH (mniej niż 0,7 ng/mL)
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Maximum age
- 45 Years
- Last updated (source)
- August 5, 2026
- Sex
- Female only
Therapies / drugs in trial
Locations (1)
Ayub Teaching Hospital
Abbottābād, Pakistan
Trial contact
Prof Dr Ruqqiya Sultana, MBBS
Dr Noman Arif, PhD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/6/2026.
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