A Study of Cyclophosphamide, Methotrexate, Fluorouracil (CMF) for People With Breast Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The purpose of this study is to find out if it is practical (feasible) to give dose-dense CMF (cyclophosphamide, methotrexate, and fluorouracil) in two standard chemotherapy regimens in people with breast cancer, age 70 and older.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 70 lat
- •Potwierdzony histologicznie rak piersi (adenocarcinoma)
- •Biopsja lub operacja przeprowadzona w ciągu 3 miesięcy przed włączeniem do badania
- •Wyniki badań HER-2/neu, receptora estrogenowego i progesteronowego dostępne
- •Wydolność ogólna pozwalająca na udział w badaniu (wynik ECOG ≤2 lub Karnofsky'ego ≥60%)
- •Prawidłowe wartości laboratoryjne: liczba neutrofili, płytki krwi, nerki i wątroba
✗ Disqualifies
- •Rak piersi w stadium IV (przerzuty odległe)
- •Rak HER-2 dodatni (3+/amplifikowany)
- •Ocena stanu zdrowia wskazująca na znaczną słabość (CARG score ≥4)
- •Chemioterapia w ciągu ostatniego roku przed włączeniem do badania
Simplified criteria — AI translation
Trial details
- Minimum age
- 70 Years
- Last updated (source)
- August 17, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (7)
Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)
Basking Ridge, United States
Memorial Sloan Kettering at Monmouth (Limited Protocol Activities)
Middletown, United States
Memorial Sloan Kettering at Bergen (Limited Protocol Activities)
Montvale, United States
Memorial Sloan Kettering Suffolk-Commack (Limited Protocol Activities)
Commack, United States
Memorial Sloan Kettering at Westchester (Limited Protocol Activities)
Harrison, United States
Memorial Sloan-Kettering Cancer Center (All Protocol Activities)
New York, United States
Memorial Sloan Kettering at Nassau (Limited Protocol Activities)
Uniondale, United States
Trial contact
Pamela Drullinsky, MD
Koshy Alexander, MD, MBA
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/18/2026.
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