RecruitingPhase IIEN original

CD19/CD22 CAR-T Consolidation in R/R Aggressive B-Cell Lymphoma After Second-Line Therapy

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The purpose of this study is to determine the efficacy and safety of CD22/CD19-targeted CAR-T cell immunotherapy as consolidation therapy after second-line treatment in patients with high-risk aggressive B-cell lymphoma.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Rozpoznanie dużokomórkowego chłoniaka B-komórkowego potwierdzonehistologicznie lub cytologicznie
  • Chłoniak wykazuje dodatnie białka CD19 i/lub CD22
  • Pełna remisja choroby po drugiej linii chemioterapii osiągnięta w ciągu ostatnich 3 miesięcy
  • Wiek od 18 do 85 lat
  • Dobry stan ogólny pacjenta (skala ECOG 0-2)
  • Przewidywana długość przeżycia powyżej 3 miesięcy
  • Wystarczające parametry krwi: hemoglobina ≥60 g/L, neutrofile ≥1000/μl, płytki ≥45000/μl
  • Obecność czynników ryzyka takich jak mutacje genetyczne lub zaawansowana postać chłoniaka

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Maximum age
85 Years
Last updated (source)
August 21, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

Chinese PLA General Hospital, Beijing, Beijing 100853

Beijing, China

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/22/2026.

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