Torvutatug Samrotecan With or Without Bevacizumab as Maintenance Treatment of Platinum-sensitive Relapsed Epithelial Ovarian Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The purpose of this study is to measure the efficacy and safety of torvutatug samrotecan (torvu-sam) with or without bevacizumab compared to standard of care (SoC) as maintenance treatment in participants with platinum-sensitive relapsed ovarian cancer (PSR OC)
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Potwierdzony guzowaty nowotwór wysokiego stopnia złośliwości w jajniku, jajowodzie lub osierdziu
- •Otrzymanie wcześniej 1-2 linii chemioterapii
- •Nawrót choroby co najmniej 6 miesięcy po ostatniej chemioterapii platynowej
- •Ukończenie 4-6 cykli chemioterapii platynowej w obecnym leczeniu
- •Brak progresji choroby po zakończeniu chemioterapii platynowej
- •Jeśli pacjent ma mutację BRCA, musi wcześniej otrzymać inhibitor PARP (o ile nie ma przeciwwskazań)
✗ Disqualifies
- •Nowotwory nieepithelialne, graniczne, jasnokomórkowe lub śluzowe, karcinosarkoma
- •Historia zapalenia płuc lub międzymięszakowego zapalenia płuc wymagającego sterydów lub tlenu
- •Niezagojone rany, aktywne wrzody lub złamania kości (nie dotyczy pacjentów bez bevacizumabu)
- •Aktywna niedrożność jelit (nie dotyczy pacjentów bez bevacizumabu)
- •Poprzednia terapia ukierunkowana na FRα lub chemioterapia ze sprzężonym przeciwciałem
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- October 16, 2026
- Sex
- Female only
Therapies / drugs in trial
Locations (124)
Research Site
Anchorage, United States
Research Site
Miami, United States
Research Site
Indianapolis, United States
Research Site
Shreveport, United States
Research Site
Columbia, United States
Research Site
Ann Arbor, United States
Research Site
Detroit, United States
Research Site
Albany, United States
Research Site
Bay Shore, United States
Research Site
Buffalo, United States
Research Site
Greenlawn, United States
Research Site
New Hyde Park, United States
Research Site
New York, United States
Research Site
New York, United States
Research Site
Rego Park, United States
Research Site
Cleveland, United States
Research Site
Cleveland, United States
Research Site
Columbus, United States
Research Site
Mayfield Heights, United States
Research Site
Oklahoma City, United States
Research Site
Philadelphia, United States
Research Site
Willow Grove, United States
Research Site
Houston, United States
Research Site
Salt Lake City, United States
Research Site
Norfolk, United States
Research Site
Morgantown, United States
Research Site
Auchenflower, Australia
Research Site
Blacktown, Australia
Research Site
Clayton, Australia
Research Site
Liverpool, Australia
Research Site
Porto Alegre, Brazil
Research Site
São Caetano do Sul, Brazil
Research Site
São José do Rio Preto, Brazil
Research Site
São José dos Campos, Brazil
Research Site
São Paulo, Brazil
Research Site
Teresina, Brazil
Research Site
Vitória, Brazil
Research Site
Abbotsford British Columbia, Canada
Research Site
Montreal, Canada
Research Site
Montreal, Canada
Research Site
Beijing, China
Research Site
Chengdu, China
Research Site
Chengdu, China
Research Site
Guangdong Province, China
Research Site
Guangzhou, China
Research Site
Hangzhou, China
Research Site
Hangzhou, China
Research Site
Nanchang, China
Research Site
Wuhan, China
Research Site
Wuhan, China
Research Site
Wuhan, China
Research Site
Zhengzhou, China
Research Site
Bad Homburg, Germany
Research Site
Bonn, Germany
Research Site
Brandenburg, Germany
Research Site
Dresden, Germany
Research Site
Düsseldorf, Germany
Research Site
Essen, Germany
Research Site
Gütersloh, Germany
Research Site
Halle, Germany
Research Site
Hamburg, Germany
Research Site
Homburg, Germany
Research Site
Kassel, Germany
Research Site
Mainz, Germany
Research Site
Mannheim, Germany
Research Site
Münster, Germany
Research Site
Schweinfurt, Germany
Research Site
Wiesbaden, Germany
Research Site
Wuppertal, Germany
Research Site
Ahmedabad, India
Research Site
Bangalore, India
Research Site
Gurgaon, India
Research Site
Kottayam, India
Research Site
Madurai, India
Research Site
Nashik, India
Research Site
Nashik, India
Research Site
New Delhi, India
Research Site
Vadodara, India
Research Site
Milan, Italy
Research Site
Milan, Italy
Research Site
Monza, Italy
Research Site
Naples, Italy
Research Site
Rome, Italy
Research Site
Torino, Italy
Research Site
Treviso, Italy
Research Site
Chiba, Japan
Research Site
Fukuoka, Japan
Research Site
Fukushima, Japan
Research Site
Gifu, Japan
Research Site
Hidaka-shi, Japan
Research Site
Ichihara, Japan
Research Site
Kagoshima, Japan
Research Site
Kobe, Japan
Research Site
Kōtoku, Japan
Research Site
Kurume-shi, Japan
Research Site
Kyoto, Japan
Research Site
Minatoku, Japan
Research Site
Natori-shi, Japan
Research Site
Sagamihara-shi, Japan
Research Site
Shinjuku-ku, Japan
Research Site
Suita-shi, Japan
Research Site
Toyoake-shi, Japan
Research Site
Yokohama, Japan
Research Site
Goyang-si, South Korea
Research Site
Seoul, South Korea
Research Site
Seoul, South Korea
Research Site
Seoul, South Korea
Research Site
Seoul, South Korea
Research Site
A Coruña, Spain
Research Site
Barakaldo, Spain
Research Site
Barcelona, Spain
Research Site
Granollers, Spain
Research Site
Madrid, Spain
Research Site
Madrid, Spain
Research Site
Kaohsiung City, Taiwan
Research Site
Taichung, Taiwan
Research Site
Taichung, Taiwan
Research Site
Tainan, Taiwan
Research Site
Taipei, Taiwan
Research Site
Bangkok, Thailand
Research Site
Bangkok, Thailand
Research Site
Bangkok, Thailand
Research Site
Hat Yai, Thailand
Research Site
Muang, Thailand
Trial contact
AstraZeneca Clinical Study Information Center
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/17/2026.
You can help another person
We fund the Radar, this site, and the development of our Grosz dla Życia fundraising platform from donations and our own resources. Every contribution, even a small one, really helps.