Dynamic Risk Prediction of Severe Myelosuppression in Nasopharyngeal Carcinoma
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This multicenter, prospective, observational cohort study aims to evaluate a previously developed dynamic risk prediction model for severe treatment-related myelosuppression in patients with nasopharyngeal carcinoma receiving systemic therapy. The model is designed to estimate the risk of grade 3 or higher anemia, thrombocytopenia, and leukopenia or neutropenia during treatment. Eligible adult patients with histologically confirmed nasopharyngeal carcinoma will be consecutively enrolled at participating centers. Before each cycle of systemic therapy, routinely available clinical and laboratory data will be collected and used to generate updated risk predictions. Patients will be followed throughout systemic therapy and for 28 days after the last treatment. This is an observational study. Treatment and supportive care will be determined by treating physicians according to routine clinical practice. Model predictions will be used only for research evaluation and will not be used to guide or modify patient treatment. The study will evaluate the predictive performance and clinical applicability of the model across multiple centers.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat
- •Potwierdzony w badaniu histologicznym rak nosogardła
- •Kwalifikacja do leczenia systemowego (chemioterapii) według lekarza
- •Dobrowolna zgoda na uczestnictwo w badaniu
✗ Disqualifies
- •Niestabilna choroba serca wymagająca leczenia
- •Słabo kontrolowana cukrzyca (bardzo wysoki poziom cukru na czczo)
- •Zaburzenia psychiatryczne
- •Historia ciężkich alergii
- •Inne poważne niekontrolowane choroby
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 15, 2026
- Sex
- No restrictions
Locations (1)
Nanfang Hospital, Southern Medical University
Guangzhou, China
Trial contact
Jian Guan
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/16/2026.
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