Metabolomics and Transcriptomics of Low- and High-Grade Gliomas
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The goal of this observational study is to better define the molecular profile of rare brain tumors (gliomas) based on the levels of their metabolites and transcripts (the intermediate step between DNA information and proteins). The main question it aims to answer is to identify new brain tumour subgroups of clinical relevance that might explain the very different history these patients might follow. Additionally, studies on gliomas require cellular cultures and animal models for the development of new medications, but these models are still scarce and rudimental for many types of gliomas. The second aim of this study is to implement better models for these tumors, for a more effective development of new medications. Patients enrolled in this study will not undergo any additional procedures with respect to those necessary for gold-standard management of these brain tumors. A small sample of the resected tumour will be used for advanced analyses investigating the metabolic and transcriptomic profile and used for temptative establishment of cellular cultures and animal models of these pathologies.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat
- •Zdiagnozowany guz mózgu potwierdzony badaniami obrazowymi (MRI lub PET)
- •Pacjent zakwalifikowany do operacyjnego leczenia guza
- •Zgoda na udział w badaniu
- •Dostęp do pełnej historii medycznej pacjenta
✗ Disqualifies
- •Wiek poniżej 18 lat
- •Niemożność zrozumienia badania lub udzielenia świadomej zgody
- •Ciąża lub karmienie piersią
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 22, 2026
- Sex
- No restrictions
Locations (1)
IRCCS Galeazzi-Sant'Ambrogio
Milan, Italy
Trial contact
Marco Rossi, MD
Direzione Scientifica IRCCS Galeazzi-Sant'Ambrogio, Milano
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/23/2026.
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