Cemiplimab and Quad Shot Radiation for Cutaneous Squamous Cell Carcinoma in the Head and Neck
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The goal of this clinical trial is to learn if the combination of the drug cemiplimab along with a short course of radiation therapy called Quad Shot can be successfully given in several rounds to elderly or frail patients with head and neck skin cancers. The main question it aims to answer is: \- Can care providers successfully deliver at least 6 rounds of cemiplimab and 3 rounds of Quad Shot radiation to patients? Patients will: * Be given cemiplimab every 3 weeks for a total of up to 8 doses * Be given Quad Shot radiation (four treatments over two days) every 3 weeks for a total of up to 4 rounds
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Zaawansowany rak skóry (płaskonabłonkowy) w okolicy głowy i szyi
- •Brak wcześniejszego leczenia lekami systemowymi (chemioterapia, terapia celowana lub immunoterapia)
- •Pacjent uznany za niezdolny do operacji lub standardowej radioterapii z powodu wieku powyżej 70 lat lub poważnych chorób towarzyszących
- •Co najmniej jedno mierzalne ognisko nowotworu
- •Dostępna próbka tkanki guza do badań laboratoryjnych
- •Prawidłowe wyniki podstawowych badań krwi i funkcji organów
- •Wiek co najmniej 18 lat
- •Zgoda na uczestnictwo w badaniu
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- October 13, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (1)
Washington University Medical Center
St Louis, United States
Trial contact
Barbara Murphy, M.D.
Zachary Kohutek, M.D., Ph.D.
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/14/2026.
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