RecruitingNot applicableEN originalColorectal cancer

Low Load Blood Flow Restriction Resistance Training in Colorectal Cancer Related Sarcopenia

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

PURPOSE: To investigate the effects of low-load resistance training combined with blood flow restriction on muscle strength, functional performance, and cancer-related fatigue in colorectal cancer survivors with probable sarcopenia. BACKGROUND: Muscle weakness and cancer-related fatigue are prevalent in colorectal cancer survivors with probable sarcopenia and are associated with adverse outcomes (Brown et al., 2022; Caan et al., 2018). High-load resistance training is often poorly tolerated in this population (Schmitz et al., 2019). Although low-load resistance training with blood flow restriction shows promise, CRC-specific randomized evidence remains limited (Patterson et al., 2019; Arnold et al., 2017). HYPOTHESES: It is hypothesized that low-load blood flow restriction resistance training will lead to significant improvements in muscle strength and functional performance, and a significant reduction in cancer-related fatigue in colorectal cancer survivors with probable sarcopenia. RESEARCH QUESTION: Does low-load blood flow restriction resistance training will lead to significant improvements in muscle strength and functional performance, and a significant reduction in cancer-related fatigue in colorectal cancer survivors with probable sarcopenia?

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • •Diagnoza raka jelita grubego ze słabością mięśni
  • •Wiek 40-59 lat
  • •Słaba siła mięśni (potwierdzzona testem wstawania z krzesła ponad 15 sekund)
  • •Aktualnie w trakcie chemioterapii/radioterapii lub po operacji, w stabilnym stanie zdrowia
  • •Zatwierdzenie lekarza do udziału w ćwiczeniach nadzorowanych
  • •Zdolność do wykonywania poleceń i ukończenia testów

✗ Disqualifies

  • •Przeciwwskazania do ćwiczeń siłowych lub ograniczenia przepływu krwi
  • •Niekontrolowana choroba serca lub wysokie ciśnienie krwi
  • •Niedawne zakrzepy krwi lub zatory
  • •Poważne choroby naczyń w nogach
  • •Niekontrolowane powikłania leczenia (np. ciężka anemia lub infekcja)
  • •Przerzuty raka do kości w dolnych kończynach
  • •Zaburzenia neurologiczne lub mięśniowo-szkieletowe uniemożliwiające bezpieczny udział

Simplified criteria — AI translation

Trial details

Minimum age
40 Years
Maximum age
59 Years
Last updated (source)
October 14, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

Private Clinics

Cairo, Egypt

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/15/2026.

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