Pabociclib, Endocrine(or ET + CDK4/6 inhibitors), Talazoparib, Atezolizumab

1 clinical trials involving this therapy/drug

This is not medical advice - consult your oncologist

Descriptions are automatically translated with AI assistance. Always verify details in the original on ClinicalTrials.gov and consult your treating physician.

RecruitingPhase IIBreast cancerHormone receptor positive (HR+)Metastatic / advanced

PALbociclib Endocrine Therapy Followed by Talazo Vs. Talazoz-Atezo Study

NCT04819243ClinicalTrials.gov ↗

This study is a prospective, two-arm, randomized phase II study of talazoparib versus talazoparib plus atezolizumab in ER+ premeonopausal women with metastatic breast cancer harboring HRD scar 1st line treatment: GnRH agonist + Aromatase Inhibitor(AI) + Palbociclib 28 days after the last treatment of 1st line treatment(., randomization for 2nd line treatment is conducte to arm A(Talazoparib+Atezolizumab) and arm B(Talazoparib monotherapy)

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