RGT-490

1 clinical trials involving this therapy/drug

This is not medical advice - consult your oncologist

Descriptions are automatically translated with AI assistance. Always verify details in the original on ClinicalTrials.gov and consult your treating physician.

RecruitingPhase IBreast cancerOvarian cancerCervical cancerOther cancersHER2 positiveHormone receptor positive (HR+)Metastatic / advanced

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

NCT07524322ClinicalTrials.gov ↗

This is a phase 1/1b, open-label, multicenter study consisting of sequential parts designed to evaluate the safety, tolerability, and effects pharmacokinetic (PK) profile, and antitumor activity of RGT-490, an investigational oral therapy, in adults with locally advanced or metastatic solid tumors including breast cancer. Participants enrolled in the study have advanced disease that is not amendable to curative treatment and whose tumors harbor alterations in the PI3KCA gene.

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