RecruitingPhase IIEN originalMelanoma

Nodal Radiation Therapy for Sentinel Lymph Node Positive Melanoma

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This phase II trial seeks to determine the role of nodal radiation therapy after sentinel lymph node biopsy (SLNB) for patients with high risk sentinel lymph node positive melanoma who are planned for immunotherapy without completion lymph node dissection. Prior studies of patients with more advanced melanoma have shown nodal radiation therapy can decrease the risk of nodal recurrence but it is not known if this same benefit will be seen in patients with high risk sentinel lymph node positive disease who are planned for immunotherapy.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Planowana immunoterapia po operacji
  • Brak zmian przerzutowych w innych organach
  • Potwierdzony czerniak w węźle wartowniczym z czynnikami wysokiego ryzyka
  • Możliwość regularnych wizyt kontrolnych
  • Zgoda na udział w badaniu na piśmie
  • Oczekiwana długość życia ponad 6 miesięcy
  • Osoby w wieku reprodukcyjnym stosują skuteczną antykoncepcję

✗ Disqualifies

  • Już wykonane całkowite usunięcie węzłów chłonnych w tej okolicy
  • Przerzuty do odległych organów
  • Wcześniejsza radioterapia na terenie, który miałby być teraz napromieniany
  • Ciąża
  • Osoby niepełnoletnie

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
August 10, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (3)

Baptist - MD Anderson Cancer Center

Jacksonville, United States

Cooper Hospital UNIV MED CTR.

Camden, United States

M D Anderson Cancer Center

Houston, United States

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/11/2026.

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