Multiple Intracerebral Doses of Neural Stem Cell-Based Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade Gliomas
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This phase I trial studies the safety of giving multiple intracerebral doses of NSC-CRAd-S-pk7 to treat patients with glioblastoma at first recurrence. NSC-CRAd-S-pk7 consists of neural stem cells that can target glioblastoma cells and carry a virus, which can kill cancer cells. Giving multiple doses of NSC-CRAd-S-pk7 may kill more tumor cells.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat
- •Ogólna sprawność organizmu pozwalająca na normalne codzienne aktywności (co najmniej 70%)
- •Oczekiwana długość życia co najmniej 3 miesiące
- •Potwierdzony glejak złośliwy, który powrócił po poprzednim leczeniu
- •Guz znajduje się w górnej części mózgu (supratentorialnie)
- •Guz powrócił po wcześniejszym promieniowaniu i chemioterapii
- •Pacjent wymaga operacji usunięcia guza
- •Wyniki badań krwi w normie (liczba białych krwinek, płytki, funkcja wątroby i nerek)
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 9, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (4)
City of Hope Medical Center
Duarte, United States
Standford University
Stanford, United States
Northwestern University
Chicago, United States
Wake Forest University
Winston-Salem, United States
Trial contact
Jana L. Portnow
Jana L. Portnow, MD
PRINCIPAL_INVESTIGATOR
Melanie H Hayden Gephart, MD
Glenn Lesser, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/10/2026.
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