A Study of pCAR-19B in the Treatment of CD19-positive Relapsed/Refractory B-ALL in Children and Adolescents
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This is a phase II clinical study to evaluate the safety and efficacy of pCAR-19 B cell autologous infusion preparation in the treatment of CD19-positive relapsed/refractory B-cell acute lymphoblastic leukemia.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Pacjent lub jego opiekun wyraża zgodę na udział w badaniu i podpisuje dokument świadomej zgody
- •Rozpoznana białaczka limfoblastyczna, która nie reaguje na chemioterapię lub powróciła po leczeniu
- •Potwierdzenie obecności markera CD19 w komórkach białaczki
- •Odpowiednia funkcja serca - wyrzutność lewej komory serca co najmniej 50%
- •Odpowiednia funkcja nerek - wartości kreatyniny w normie lub nieznacznie podwyższone
- •Odpowiednia funkcja wątroby - wartości enzymów wątrobowych w normie lub nieznacznie podwyższone
- •Nasycenie krwi tlenem co najmniej 92% bez dodatkowego tlenu
- •Oczekiwana długość życia co najmniej 12 tygodni
Simplified criteria — AI translation
Trial details
- Minimum age
- 3 Years
- Maximum age
- 21 Years
- Last updated (source)
- September 15, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (16)
Beijing Children's Hospital.Capital Medical University
Beijing, China
Beijing GoBroad Boren Hospital
Beijing, China
Children's Hospital of Chongqing Medical University
Chongqing, China
Shenzhen Children's Hospital
Shenzhen, China
Pediatric Hematology department of Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology
Wuhan, China
Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology
Wuhan, China
Xiehe Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology
Wuhan, China
The Second Xiangya Hospital, Central South University
Changsha, China
Affiliated Drum Tower Hospital, Medical School of Nanjing University
Nanjing, China
Jiangsu Province Hospital
Nanjing, China
Children's Hospital Of Soochow University
Suzhou, China
The First Affiliated Hospital of Nanchang University
Nanchang, China
West China Second University Hospital,Sichuan University
Chengdu, China
Institute Of Hematology&Blood Diseases Hospital,Chinese Academy Of Medicai Sciences
Tianjin, China
Children's Hospital, Zhejiang University School of Medicine
Hangzhou, China
The First Affiliated Hospital of Zhengzhou University
Henan, China
Trial contact
Tianyou Wang, M.D
Yicheng Zhang, M.D
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/16/2026.
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