Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This phase II trial tests the safety of positron emission tomography (PET) guided stereotactic body radiation therapy (SBRT) and how well it works to treat non-small cell lung cancer (NSCLC), melanoma, and renal cell carcinoma (RCC) that has up to 5 sites of progression (oligoprogression) compared to standard SBRT. SBRT uses special equipment to position a patient and deliver radiation to tumors with high precision. This method may kill tumor cells with fewer doses over a shorter period and cause less damage to normal tissue. A PET scan is an imaging test that looks at your tissues and organs using a small amount of a radioactive substance. It also checks for cancer and may help find cancer remaining in areas already treated. Using a PET scan for SBRT planning may help increase the dose of radiation given to the most resistant part of the cancer in patients with oligoprogressive NSCLC, melanoma, and RCC.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek 18 lat lub więcej
- •Diagnoza potwierdzona histologicznie lub cytologicznie
- •Rozpoznany rak płuca bez drobnych komórek (NSCLC) z 1-5 ogniskami progresji podczas lub po leczeniu immunoterapią
- •Stan ogólny pacjenta poniżej lub równy 2 w skali ECOG
- •Ogniska choroby dostępne do radioterapii, każde co najmniej 1 cm
- •Pierwotny guz kontrolowany przez co najmniej 3 miesiące
- •Spodziewana długość życia co najmniej 3 miesiące
- •Zgoda na użycie tkanki z biopsji do badań
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- August 31, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (2)
City of Hope Medical Center
Duarte, United States
City of Hope at Irvine Lennar
Irvine, United States
Trial contact
Arya Amini
Arya Amini
PRINCIPAL_INVESTIGATOR
Arya Amini, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/1/2026.
You can help another person
We fund the Radar, this site, and the development of our Grosz dla Życia fundraising platform from donations and our own resources. Every contribution, even a small one, really helps.