Adaptive Radiation Therapy (ART) Stereotactic Ablative Body Radiotherapy (SABR) for Primary Localized Prostate Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This clinical trial evaluates changes in quality of life after two treatments with near margin-less adaptive radiation therapy (ART) compared to five treatments with standard stereotactic ablative body radiotherapy (SABR) in patients with prostate cancer that has not spread to other parts of the body (localized). ART is a type of radiation therapy that uses information gathered during the treatment cycle to inform, guide, and alter future radiation treatments with respect to location and dose. It may be able to deliver radiation to the site of disease over a shorter time and with smaller margins (less treatment delivered to nearby healthy tissues). SABR is a type of external radiation therapy that uses special equipment to position a patient and precisely deliver radiation to tumors in the body (except the brain). The total dose of radiation is divided into smaller doses given over several days. This type of radiation therapy helps spare normal tissue. Shorter duration near margin-less ART may be just as effective at treating patients with localized prostate cancer but have less quality of life side effects than standard SABR.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Pacjenci płci męskiej, w wieku 18 lat lub starsi.
- •Rak prostaty potwierdzony badaniem histologicznym.
- •Rak prostaty o niskim lub pośrednim ryzyku (wg klasyfikacji NCCN).
- •Stan ogólny pacjenta pozwalający na udział w badaniu (ECOG ≤ 2).
- •Możliwość samodzielnego lub z pomocą wypełniania ankiet.
- •Zgoda na udział w badaniu i wizyty kontrolne.
✗ Disqualifies
- •Rak prostaty o bardzo niskim, wysokim lub bardzo wysokim ryzyku (wg klasyfikacji NCCN).
- •Wcześniejsze leczenie raka prostaty (np. operacja, inne rodzaje radioterapii, krioterapia).
- •Wcześniejsze zabiegi na drogach moczowych.
- •Rak prostaty, który rozprzzenił się na inne części ciała (przerzuty).
- •Przeciwwskazania do radioterapii.
- •Przyjmowanie chemioterapii w trakcie badania.
- •Inne nowotwory w ciągu ostatnich 5 lat (z pewnymi wyjątkami).
- •Choroby uniemożliwiające świadome podejmowanie decyzji lub stosowanie się do zasad badania.
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- July 30, 2026
- Sex
- Male only
Therapies / drugs in trial
Locations (5)
Mayo Clinic Health System in Albert Lea
Albert Lea, United States
Mayo Clinic Health System-Mankato
Mankato, United States
Mayo Clinic in Rochester
Rochester, United States
Mayo Clinic Health System-Eau Claire
Eau Claire, United States
Mayo Clinic Health System-Franciscan Healthcare
La Crosse, United States
Trial contact
Clinical Trials Referral Office
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/31/2026.
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