Cardiopulmonary Function and Cerebral Blood Flow in Hodgkin Lymphoma Survivors
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
SURVIVORS Study participants are being asked to take part in this research study called HODNIRS because the participant is a survivor of Hodgkin Lymphoma (HL) treated with chest radiation and bleomycin at St. Jude Children's Research Hospital. The study is being done to help investigators understand the link between long term effects of chest radiation and bleomycin for HL and brain function in survivors. Primary Objective To evaluate dynamic changes in CBF and oxygenation during exercise with Near Infrared Spectroscopy (NIRS) in HL survivors and non-cancer controls matched for age, sex, race, and ethnicity. . Secondary Objectives To examine the degree of CO2 clearance (DLCO/ETCO2) during rest and exercise in Hodgkin Lymphoma (HL) survivors compared to non-cancer controls matched for age, sex, race, and ethnicity. CONTROLS Volunteers are being asked to take part in this research study because they are non-first degree relative or friend of someone who received treatment for a childhood cancer or similar illness at St. Jude Children's Research Hospital or are an employee/affiliate of St. Jude Children's Research Hospital and have agreed to be a St. Jude Life Cohort Study (SJLIFE) community control.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Ukończona terapia bleomycyną i/lub promieniowaniem klatki piersiowej w leczeniu chłoniaka Hodgkina
- •Diagnoza postawiona przed 21. rokiem życia, obecnie co najmniej 18 lat, co najmniej 2 lata po zakończeniu leczenia
- •Uczestnik programu SJLIFE lub ACT/SJLIFE
- •Znajomość języka angielskiego
✗ Disqualifies
- •Historia promieniowania czaszki lub całego ciała
- •Historia chemioterapii podawanej bezpośrednio do opon mózgowo-rdzeniowych lub wysokich dawek przez żyły
- •Historia urazu głowy lub rozpoznana choroba genetyczna wpływająca na funkcje umysłowe
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 1, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (1)
St. Jude Children's Research Hospital
Memphis, United States
Trial contact
Nicholas Phillips, PhD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/2/2026.
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