RecruitingPhase IEN originalLeukemia

Ziftomenib Maintenance Post Allo-HCT

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The purpose of this study is to test the safety, effects, and recommended dose of an investigational drug, ziftomenib, in addition to the standard treatment on blood cancer with Allogeneic Hematopoietic Cell Transplantation (allo-HCT). This study plans to learn more about ziftomenib, which targets and inhibits negative interactions within cancer cells related to AML, when given after allo-HCT, to determine if it improves outcomes following allo-HCT. The name of the study drug involved in this study is: • Ziftomenib

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • •Wiek 18 lat lub więcej
  • •Potwierdzona diagnosis ostre białaczki szpikowej (AML)
  • •Remisja nowotworu (brak lub bardzo mało komórek rakowych)
  • •Obecność mutacji genetycznej KMT2A lub NPM1
  • •Będzie to pierwsze przeszczepienie szpiku kostnego z darczyńcy
  • •Leczenie innymi lekami przed przeszczepem jest dozwolone

✗ Disqualifies

  • •Powrót białaczki lub jej postęp podczas leczenia lekami menin inhibitorami przed przeszczepem

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
October 6, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (2)

Massachusetts General Hospital

Boston, United States

Ohio State University Wexner Medical Center- James Cancer Hospital

Columbus, United States

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/7/2026.

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