Study of Pembrolizumab, Carboplatin, Paclitaxel, and Radiation for the Treatment of Early-Stage Anal Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
A single arm phase II study of pembrolizumab, carboplatin, paclitaxel, and radiation for the treatment of early-stage anal cancer. There are 2 treatments phases and then surveillance. The first treatment phase is the chemoradiation phase (Cycle 1-6, weekly cycles) which is followed by the maintenance phase (Cycle 7-14, 6 week cycles).
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat
- •Diagnoza raka płaskonabłonkowego odbytnicy w wczesnym lub średnim zaawansowaniu (stadium I-IIIA, lub IIIB/C jeśli guz poniżej 5 cm)
- •Pacjent nie otrzymał jeszcze żadnego leczenia raka odbytnicy
- •Niezakwalifikowany do standardowego leczenia (5-fluorouracyl i mitomycyna-C z promieniowaniem) według lekarza
- •Wystarczająca funkcja narządów (prawidłowe wyniki krwi, nerek i wątroby)
- •Dostępna próbka tkanki guza do badań (archiwalna lub pobrana nowo)
- •Kobiety w wieku rozrodczym - ujemny test ciąży przed włączeniem do badania
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- October 7, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (5)
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
Indianapolis, United States
University of Iowa Hospitals and Clinics
Iowa City, United States
University of Maryland
Baltimore, United States
Rutgers Cancer Institute of New Jersey
New Brunswick, United States
University of Wisconsin
Madison, United States
Trial contact
Dustin Deming, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/29/2026.
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