CfDNA in Hereditary And High-risk Malignancies 2

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The goal of this study is to understand the performance of an experimental blood test that aims to detect early tumors in patients with hereditary cancer syndromes. If this new blood test is accurate, it could be used to screen patients for cancer and allow for earlier cancer detection. The study will compare cancer detection rates between those receiving the new blood test and those receiving standard care, assess if the test leads to earlier cancer diagnosis, and evaluate its impact on patient outcomes. The study will also use questionnaires and interviews to understand how patients feel about the blood test, its incorporation into routine medical care, and perceptions of the medical value of test results. This research could lead to more effective and less invasive cancer screening for high-risk individuals.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • •Potwierdzona diagnoza dziedzicznego raka piersi i jajnika, zespołu Lyncha, neurofibromatozy typu 1, zespołu Li-Fraumeni, mutacji PALB2 lub dziedzicznego raka żołądka
  • •Otrzymywanie standardowego nadzoru lekarskiego w kierunku raka przez swoją placówkę ochrony zdrowia
  • •Podpisana i datowana zgoda na udział w badaniu

✗ Disqualifies

  • •Rak zdiagnozowany i leczony w ciągu ostatnich 3 lat przed rozpoczęciem badania
  • •Rak zdiagnozowany ponad 3 lata temu, ale nigdy nie leczony
  • •Badania w kierunku podejrzenia raka w chwili obecnej
  • •Brak możliwości poddawania się co 4 miesiące pobieraniu próbek krwi

Simplified criteria — AI translation

Trial details

Maximum age
90 Years
Last updated (source)
October 8, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (8)

BC Cancer Agency

Vancouver, Canada

Newfoundland and Labrador Health Services (previously Eastern Health)

St. John's, Canada

IWK Health Centre

Halifax, Canada

The Hospital for Sick Children

Toronto, Canada

Sinai Health System

Toronto, Canada

University Health Network

Toronto, Canada

Women's College Hospital

Toronto, Canada

Jewish General Hospital

Montreal, Canada

Trial contact

Julia Sobotka, MSc

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/9/2026.

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