RecruitingPhase IIEN originalOther cancers

PULSO Trial: Pulsed Low-Dose-Rate (PLDR) Radiation Chemoradiation (CRT) vs. Standard CRT for Esophageal Cancer

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This is a prospective, randomized, open-label, two-arm phase 2 trial that will evaluate whether the use of Pulsed Low-Dose-Rate radiation technique, as compared to standard radiation, is associated with reduced rates of clinically significant esophagitis during and following chemoradiation.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • •Wiek powyżej 18 lat
  • •Rak przełyku w stadium II-IVb (jeśli IVb, tylko z ograniczonymi przerzutami)
  • •Leczenie chemią poprzedzające, planowana chemio-radioterapia i możliwe usunięcie przełyku
  • •Ogólny stan zdrowia pozwalający na leczenie (skala ECOG 0-2)
  • •Wystarczająca liczba krwinek i płytek w krwi
  • •Prawidłowa funkcja nerek i wątroby
  • •Kobiety w wieku rozrodczym: ujemny test ciążowy
  • •Zdolność zrozumienia informacji o badaniu i chęć uczestnictwa

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
July 28, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

Froedtert & the Medical College of Wisconsin

Milwaukee, United States

Trial contact

Medical College of Wisconsin Cancer Center Clinical Trials Office

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/29/2026.

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