RecruitingPhase IEN originalGlioma (brain cancer)

Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The researchers are doing this study to find out whether the drugs ABBV-637 and ABBV-155 are safe treatments that cause few or mild side effects when given alone or in combination with ERAS-801 in people with recurrent GBM.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • •Wiek co najmniej 18 lat w momencie podpisania zgody
  • •Potwierdzony glejak wielopostaciowy stopnia IV (WHO 2021) - nawrotowy lub progresywny po radioterapii
  • •Gen IDH typu dzikiego potwierdzony badaniem laboratoryjnym
  • •Potwierdzony wzmożony gen EGFR badaniem laboratoryjnym
  • •Mierzalne nowotwory przed operacją według kryteriów RANO
  • •Zdolność do wykonania badania MRI
  • •Nie więcej niż 2 wcześniejsze linie leczenia
  • •Odpowiedni czas od poprzednich terapii (od 2 tygodni do 6 miesięcy w zależności od rodzaju leczenia)

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
September 9, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (11)

University of California, Los Angeles (Data Collection Only)

Los Angeles, United States

University of Miami (Data collection only)

Miami, United States

Indiana University (Data Collection Only)

Indianapolis, United States

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

Basking Ridge, United States

Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

Middletown, United States

Memorial Sloan Kettering Bergen (Limited Protocol Activities)

Montvale, United States

Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)

Commack, United States

Memorial Sloan Kettering Westchester (All Protocol Activities)

Harrison, United States

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

New York, United States

Memorial Sloan Kettering Nassau (Limited Protocol Activities)

Rockville Centre, United States

University of Vermont Medical Center

Burlington, United States

Trial contact

Ingo Mellinghoff, MD

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/10/2026.

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