AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This study, the first clinical trial of AVZO-1418, aims to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, maximum tolerated dose, and antitumor activity of AVZO-1418 when administered intravenously as a monotherapy and potentially in combination therapy to patients with locally advanced or metastatic epithelial solid tumors.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek od 18 do 75 lat
- •Dobry stan ogólny (możliwość codziennych aktywności)
- •Spodziewana długość życia ponad 3 miesiące
- •Potwierdzony zaawansowany lub przerzutowy nowotwór tkanek złożonych
- •Widoczne zmiany nowotworowe mierzalne na badaniach
- •Zgoda na przekazanie wyników testów genetycznych i próbek guza
✗ Disqualifies
- •Niekontrolowane wysokie ciśnienie krwi
- •Aktywne przerzuty do mózgu
- •Historia choroby płuc spowodowanej lekami
- •Poważne problemy z sercem
- •Aktywne infekcje wymagające antybiotyków podawanych dożylnie w ciągu 2 ostatnich tygodni
- •Przeszczepienie narządu
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Maximum age
- 75 Years
- Last updated (source)
- October 16, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (27)
Avenzo Therapeutics Recruiting Site
Gilbert, United States
Avenzo Therapeutics Recruiting Site
Los Angeles, United States
Avenzo Therapeutics Recruiting Site
Los Angeles, United States
Avenzo Therapeutics Recruiting Site
Denver, United States
Avenzo Therapeutics Recruiting Site
New Haven, United States
Avenzo Therapeutics Recruiting Site
Washington D.C., United States
Avenzo Therapeutics Recruiting Site
Orlando, United States
Avenzo Therapeutics Recruiting Site
Sarasota, United States
Avenzo Therapeutics Recruiting Site
Tampa, United States
Avenzo Therapeutics Recruiting Site
Atlanta, United States
Avenzo Therapeutics Recruiting Site
Boston, United States
Avenzo Therapeutics Recruiting Site
New York, United States
Avenzo Therapeutics Recruiting Site
Philadelphia, United States
Avenzo Therapeutics Recruiting Site
Dallas, United States
Avenzo Therapeutics Recruiting Site
Houston, United States
Avenzo Therapeutics Recruiting Site
San Antonio, United States
Avenzo Therapeutics Recruiting Site
West Valley City, United States
Avenzo Therapeutics Recruiting Site
Fairfax, United States
Avenzo Therapeutics Recruiting Site
Seattle, United States
DualityBio Recruiting Site
Beijing, China
DualityBio Recruiting Site
Chongqing, China
DualityBio Recruiting Site
Harbin, China
DualityBio Recruiting Site
Zhengzhou, China
DualityBio Recruiting Site
Changsha, China
DualityBio Recruiting Site
Nanchang, China
DualityBio Recruiting Site
Shenyang, China
DualityBio Recruiting Site
Jinan, China
Trial contact
Medical Information
China DualityBio
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/29/2026.
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