Compartmentalized Postoperative Radiotherapy in Head and Neck Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
COMPORT is a multicenter phase II clinical trial evaluating a personalized approach to postoperative radiotherapy in patients with head and neck squamous cell carcinoma (HNSCC). The study investigates whether a risk-adapted, compartmentalized radiotherapy strategy can safely reduce the treatment volume, and thus the side effects, without increasing the risk of tumor recurrence. Eligible patients are those with surgically treated cancers of the oral cavity, oropharynx, larynx, or hypopharynx who have a standard indication for postoperative radiotherapy. The primary outcome is the rate of recurrence in anatomical compartments that would normally be irradiated but are intentionally omitted in this study. COMPORT aims to generate high-level evidence to support a more personalized and less toxic standard of care in postoperative head and neck cancer management.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek powyżej 18 lat
- •Rak komórek płaskorządowych jamy ustnej, gardła, krtani lub gardła dolnego usunięty chirurgicznie
- •Zalecenie do radioterapii po operacji zatwierdzone przez zespół specjalistów
- •Badania obrazowe (MRI lub CT) głowy, szyi i klatki piersiowej wykonane nie wcześniej niż 60 dni przed włączeniem
- •Możliwość bezpiecznego otrzymania standardowego leczenia
- •Ogólny stan zdrowia pozwalający na uczestnictwo w badaniu
- •Dla kobiet w wieku rozrodczym: stosowanie antykoncepcji i negatywny test ciąży
- •Poprzednia chemioterapia lub immunoterapia przed operacją jest dozwolona
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- August 27, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (3)
University Hospital of Basel
Basel, Switzerland
Inselspital, Bern University Hospital
Bern, Switzerland
University Hospital of Zurich
Zurich, Switzerland
Trial contact
Olgun Elicin, Prof. Dr. med.
Daniel H Schanne, Dr. med.
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/28/2026.
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