A Study of JNJ-98768111 in Participants With Advanced Prostate Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The purpose of Part 1 of this study is to find out how safe JNJ-98768111 is and the most suitable dose (recommended phase 2 dose \[RP2D\]) regimen(s) of JNJ-98768111. The purpose of Part 2 of this study is to find out how safe JNJ-98768111 is at the RP2D regimen(s) in participants with advanced prostate cancer (cancer of the prostate, a male reproductive gland found below the bladder, which has spread extensively to other parts of the body).
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Potwierdzony histologicznie rak gruczołowy prostaty
- •Zmiana nowotworowa widoczna w badaniach obrazowych (TK, rezonans lub badanie kości)
- •Wcześniejsze leczenie co najmniej jednym lekiem hormonalnym przeciwko receptorom androgenów
- •Podwyższone wyniki PSA (>=2 ng/mL)
- •Niezmienna hormonal terapia - pacjent musi być leczony lub miał usunięte jądra
- •Niska zawartość testosteronu we krwi
- •Postęp choroby pomimo ostatniego leczenia
- •Stan ogólny pozwalający na aktywność fizyczną (ECOG 0-1)
✗ Disqualifies
- •Brak zgody na używanie efektywnych metod antykoncepcji przez 6 miesięcy po leczeniu
- •Brak zgody na nianie bezpieczeństwa seksy (użycie prezerwatywy)
- •Zaplanowanie ojcostwa lub darowanie nasienia
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 25, 2026
- Sex
- Male only
Therapies / drugs in trial
Locations (5)
Florida Cancer Specialists & Research Institute
Sarasota, United States
Start Midwest
Grand Rapids, United States
START Mountain Region
West Valley City, United States
Rambam Health Care Campus
Haifa, Israel
Sourasky Medical Center
Tel Aviv, Israel
Trial contact
Study Contact
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/1/2026.
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