LECS Combined With LSNNS for Early Gastric Cancer (LENS Trial)
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Early gastric cancer (EGC) is traditionally treated with either endoscopic resection or standard laparoscopic gastrectomy with formal lymph node dissection. However, endoscopic resection cannot evaluate or treat regional lymph node metastasis, whereas standard surgery significantly impairs postoperative gastric physiological function and patient quality of life (QoL). The LENS trial is a prospective, single-arm clinical study designed to evaluate the feasibility, safety, and long-term efficacy of Laparoscopic and Endoscopic Cooperative Surgery (LECS) combined with Laparoscopic Sentinel Node Navigation Surgery (LSNNS) using Indocyanine Green (ICG) fluorescence tracing for patients with cT1N0M0 early gastric cancer. In this trial, eligible patients will undergo intraoperative sentinel lymph node (SN) biopsy guided by ICG. Patients with negative SN status will receive stomach-preserving surgery (primarily Non-exposed Endoscopic Wall-inversion Surgery, NEWS), while those with positive SN status will convert to standard laparoscopic gastrectomy. The primary goal is to confirm whether this combined procedure provides long-term oncological safety comparable to standard radical gastrectomy, while significantly improving postoperative gastric function, nutritional status, and quality of life.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Potwierdzony biopją nowotwór żołądka (jeden guz)
- •Wiek od 20 do 80 lat
- •Ogólny stan zdrowia dobry lub niewielkie ograniczenia (ECOG 0-1)
- •Kwalifikowani do operacji laparoskopowej
- •Świadoma zgoda na uczestnictwo w badaniu
✗ Disqualifies
- •Możliwość leczenia tylko endoskopowego (bez operacji)
- •Poważne problemy z sercem lub płucami uniemożliwiające operację
- •Ciąża
- •Alergia na barwnik ICG
- •Wcześniejsza operacja lub napromienianie górnej części brzucha
- •Inny nowotwór złośliwy w ciągu ostatnich 5 lat
Simplified criteria — AI translation
Trial details
- Minimum age
- 20 Years
- Maximum age
- 80 Years
- Last updated (source)
- October 5, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (1)
Peking University People's Hospital
Beijing, China
Trial contact
Zhidong Gao
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/6/2026.
You can help another person
We fund the Radar, this site, and the development of our Grosz dla Życia fundraising platform from donations and our own resources. Every contribution, even a small one, really helps.