CARCIK CD123/33 for Refractory/Relapsed AML and BPDCN in Children and Adults
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The purpose of this phase I/II clinical trial is to test CARCIK-CD123/33 cells to treat patients with R/R AML/BPDCN, who have otherwise exhausted conventional treatment options. In particular, this study will assess the safety and feasibility of CARCIK-CD123/33 cells infusion in adults and children with R/R AML, ahead of scheduled alloHCT.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek od 6 miesięcy do 75 lat
- •Aktywna białaczka ostra (AML) lub białaczka dendryto-komórkowa (BPDCN) z widocznymi komórkami nowotworowymi w szpiku i/lub we krwi
- •Choroba oporna na leczenie lub nawrót po co najmniej dwóch liniach terapii
- •Możliwość znalezienia dawcy szpiku (co najmniej częściowo zgodny genetycznie)
- •Komórki nowotworowe wykazujące markery CD123 i CD33 potwierdzone badaniem laboratoryjnym
- •Możliwość otrzymania przeszczepu szpiku w przyszłości
- •Zadowalająca funkcja serca i płuc
- •Zgodna informowana zgoda rodzica/opiekuna (dla dzieci) lub pacjenta
Simplified criteria — AI translation
Trial details
- Minimum age
- 6 Months
- Maximum age
- 75 Years
- Last updated (source)
- October 16, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (2)
Fondazione IRCCS San Gerardo dei Tintori
Monza, Italy
ASST Papa Giovanni XXIII
Bergamo, Italy
Trial contact
Giorgio Ottaviano, Medicine
Giovanna Lucchini, Medicine
Giorgio Antonio Ottaviano, Medicine
PRINCIPAL_INVESTIGATOR
Benedetta Rambaldi, Medicine
Benedetta Rambaldi, Medicine
PRINCIPAL_INVESTIGATOR
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/17/2026.
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